Process Analytical Technology (PAT) in Pharmaceuticals

Process Analytical technology (PAT) is an important methodology in the design of pharmaceutical manufacturing process. It’s simply a method or methods that are most necessary when producing drugs, where controls and analysis are placed to ensure the quality of raw materials used and the process in manufacturing is ideal in order to produce a final product of high and best quality. This is made possible through proper measurement and calibration of critical process which are important variables or parameters that have direct impact to the pharmaceutical production process and product quality. Pharmaceutical products have great significance in health care, which may include treatment, managing diseases and other health defect regulation, the pharmaceutical manufacture needs to put into consideration regulatory process and great engineering know how, alongside quality technology, which can stand up to the challenge as we advance in technology and science in the industry. Process analytical technology (PAT) Frame work is simply quality control.


There are factors that influences PAT frame work, ad these includes;Passage of Administration; This talks about how the drugs are taken. Some are in tablets, capsules, creams and liquid (syrup). They can be ingested through the mouth, some passed via injections, ocular, nasal, rectal etc.Pharmacokinetic characteristics of the drugs:This factor, talks about how the drugs move in the body, or interact with it. It also talks about its time of absorption, how it is distributed and how it is excreted. This can help to also know how long the drug would stay in the body or how long its effect will have on the individual.

Toxicological characteristics; This is very important as it tells how harmful a drug can be or how it affects a particular individual. This also helps in determining the method of application or administration. For example a virginal cream to top an infection cannot be swallowed because it will have a bad effect to the digestive system. Also it helps to identify drugs that can be harmful if taken by some individual in delicate health position.Chemical, physical, biopharmaceutical characteristics;This how to deal with the chemical components of the drug and how it reacts to other properties or different external environment like temperature, humidity, which has to do with mostly storage.

This tells how the drug should be packaged and this is made possible by quality assurance and process analytical technology (PAT). This creates quality products that get to the consumers. Process analytical technology (PAT) analysis goes a long way to help the health regulatory system or body in creating a standard for every pharmaceutical company on how and what they should take into consideration before their drugs hit the public.There are principles or steps to be taken into consideration when one has to deal with pharmaceutical product designing and its process in manufacturing. This principles regulates various materials and process used in production. Also because of the constant rise in technological advancement in the pharmaceutical world, and the world In general today, there have been a lot of progress when it comes to chemical composition,

density and other properties, this now creates a little set back as some other attributes may not be considered which may end up becoming harmful to the consumer when it hit the public and the streets.These are then checked by some tools, called PROCESS ANALYTICAL TECHNOLOGY TOOLS (PAT TOOLS).


Process Analytical Technology Tools (Pat Tools)

A process analytical technology tool (PAT tools) helps to limit such difficulties in understanding the materials used. Which can help to discover new and vital information of the products, both physical, chemical and biological. These tools includesPROCESS ANALYSIS: This creates a wide range of data, used for quality assurance. This provides analysis more than just the PH, humidity, pressure and temperature. It carries out test that analysis the physical, chemical and biological properties of the drugsMULTIVARIATE TOOLS: These are used for designing analysis and acquiring data in the process analytical technology (PAT) process. This is important in the process design of the final product. Process analytical technology (PAT) is very important in pharmaceuticals and also a very important process for quality control.

Security Camera Recording Systems - An Introduction to Current Technology Ever come home and noticed that something was missing; maybe an ornament or silverware and you had no way of finding out where it was or who might have taken it. Perhaps you own a business; an electronic hardware shop to be precise, you do not trust the methods with which your sales personnel are handling business and you would like to keep them on their toes with surveillance. You are in the right place if you are considering buying and installing a video surveillance system for home or office use.I am going to be discussing the different Video surveillance systems available in the market and the features of each to inform you in your purchase decision.

It is pertinent for you to know above all else that the Video Surveillance System is based on the quality of the recorded images. As at the time of writing this article there are three types of Video Surveillance Systems available: The Analog/Time Lapse Recorder (VCR) Systems, the Digital Hard Drive Recording Systems (just like a VCR with the difference being that it uses a hard drive to store videos) and the PC based Digital Video Recording Systems (DVR)


The Analog/Time Lapse Recorder The first surveillance cameras (which were time-lapse recorders) required a monitor for every camera. It has a single video input, recording incoming signal with a video tape that records between 2-960 hours of video depending on the recorder.

The video relay slowed down at a rate of one picture every 9 seconds (very slow right!). To get a clear image of what the recorded feed would look like, imagine watching people pass by through a video but instead of walking, they seem to be taking each step so slowly it would seem like they were walking 100 meters in 5 minutes.

I recommend that you set the recording duration to a time no longer than 72 hours as this would enable you record the entire weekend without having to switch tapes. The time-lapse recorder is okay if you are only going to need a single camera or you could add a video multiplexer for multiple cameras.

This will give you the advantage of recording multiple cameras on a single time-lapse recorder and monitor. Multiplexers come in two types, color or black and white. The negative is that during relay of incoming video, about half the information on the picture is lost and the total image per second for each camera reduces from nine to three seconds.

Digital Hard-drive Recorder As technology improved, manufacturers were able to come up with a new design that fuses the multiplex function of the time-lapse recorder another system that uses hard drives instead of VCR tapes to store recorded visuals (an upgrade right!).

While the software is operated internally, the high resolution for video input is hardware based and can record high-resolution video feed from more than 16 cameras at up to 160 images per second as against the time-lapse that recorded one picture every 9 seconds! As soon as the hard drive fills, the system removes the oldest videos to create space to record new images, (this is called First in First Out Video).

So the larger the hard drive, the more images that can be stored. An awesome feature of this recorder is that it allows advanced playback capabilities that ensure you find stored videos in seconds not hours as against the time-lapse recorder.

PC based Digital Video Recorder This surveillance system comprises of a computer, video capture cards and a software package. It has a far higher processing speed that relays recording of up to 480 images per second and allows full motion video to be recorded and played back on a PC.


This would mean that people who you watched on the live video feed were just as they seemed through the camera instead of watching action that has already happened. It also has options for remote viewing so that even when you are not at home or at the business place you can view everything happening in real time via an internet connectivity.I personally recommend the Digital Video Recorder. There are so many options for the PC based Digital Video Recorder and it is relatively cheaper than the other options. The cameras are so small that they you can hide them if you do not want it seen. An example here is a nanny cam.At the end of it all it comes down to your budget, the features of each and the purpose you want it to serve.

The Big FiveThings to note before developing your e-commerce app

E-commerce is a very lucrative business online and the market, though saturated, still gives new comers a chance to take a chunk from the pie. Before you do however, you must understand the field; what the consumers want and how they shop online. Most especially, you must have a good knowledge of e-commerce software’s, how they operate and what makes the difference for you to make a choice.Here is our break down of the 5 basic things you need to know when thinking of one;Understand the App flow: You need to know how your app will work. It has to be user friendly and not complicated. Work hand in hand with the app developers to ensure your app;

Registration process is seamless. E.g users can register via their social media handlesthe process as simple as possible, make navigation simple by reducing the number of screens your customers have to go throughDon’t make the sign-up process mandatory to avoid them getting turned off

Provide more than one payment method to encourage usageYour eCommerce support and Maintenance: Make sure you have a working relationship with your e-commerce development company. This is to ensure you get their buy-in when your app develops any problem and can easily access them. Expected occurrences like when your payment platform develops a problem or stops working or when the server crashes, you can contact them as they will be on standby to correct the problem. A good working relationship is paramount.

Choose the right e-commerce platform: It is expected that you must have done your homework to be able to decide the best m-commerce app development company to work with. When you understand the e-commerce platform you want to work with, the m-commerce app to use will not be a problem. Find below some of the leading eCommerce platforms you can choose from;

If you need over 13000+ modules and themes to jumpstart, grow and expand your business, then you need ‘OpenCart’. OpenCart market place is an open source PHP based online e-commerce solution that provides beautiful themes for most sectors amongst other available services common with e-commerce app.

Magneto is another flexible e-commerce platform that offers almost everything one should expect from an eCommerce site. Shopify is another well known platform that affords ease of setup. You can easily customize the look of your site ad more. It has a handy dashboard area that helps you quickly add up products.

If you want to have control to sell anything anywhere, then Woo Commerce is just what you need. It gives you the freedom to create a beautiful online store while providing a strong and robust framework to your developers.

Get a simple and fast Admin Panel: Admin panels play a vital role in your e-commerce plan. It allows you control and manage data on your platform so before choosing an e-commerce platform, make sure you understand and are able to handle the back end without any fuss or fight.

Admin panels allows you manage and control data such as inventory, promo codes, payment status, view, add and delete email users, amongst other services. s

make sure you understand and are able to handle the back end without any fuss or fight. Admin panels allows you manage and control data such as inventory, promo codes, payment status, view, add and delete email users, amongst other services.

Make sure you do all five. It is essential that you carry out research about any business you want to go in and also about partners you will be collaborating with. It is also essential that you understand the business and know all the software that will enhance your business. Make sure you have a good knowledge of mobile apps before you go to a mobile app development agency.